Structures deposited with the PDB
(69 so far)
 
Anti-bacterial drug discovery
3PBN - Penicillin Binding Protein 3 from Pseudomonas aeruginosa
3PBO - Penicillin Binding Protein 3 from Pseudomonas aeruginosa
3PBQ - Penicillin Binding Protein 3 from Pseudomonas aeruginosa
3PBR - Penicillin Binding Protein 3 from Pseudomonas aeruginosa
3PBS - Penicillin Binding Protein 3 from Pseudomonas aeruginosa
3PBT - Penicillin Binding Protein 3 from Pseudomonas aeruginosa
2WIU - HipB in complex with HipA (Escherichia coli) - modified by mercury ions
2C00 - Biotin carboxylase (Pseudomonas aeruginosa) apo-form
2J9G - Biotin carboxylase (Escherichia coli) with AMP-PNP and ADP
2VPQ - Biotin carboxylase (Staphylococcus aureus) with AMP-PNP
2VQD - Biotin carboxylase (Pseudomonas aeruginosa) with AMP-PCP
2VR1 - Biotin carboxylase (Escherichia coli) with AMP-PCF2P
2RHQ - Phenylalanine tRNA synthetase in complex with inhibitor
2RHS - Phenylalanine tRNA synthetase in complex with inhibitor
2GG0 - Methionine aminopeptidase with inhibitor
2GG2 - Methionine aminopeptidase with inhibitor
2GG3 - Methionine aminopeptidase with inhibitor
2GG5 - Methionine aminopeptidase with inhibitor
2GG7 - Methionine aminopeptidase with inhibitor
2GG8 - Methionine aminopeptidase with inhibitor
2GG9 - Methionine aminopeptidase with inhibitor
2GGB - Methionine aminopeptidase with inhibitor
2GGC - Methionine aminopeptidase with inhibitor

Bacterial type III secretion and flagellum assembly
1G9U - YopM effector protein from Yersinia pestis
1JL5 - YopM effector protein from Yersinia pestis
1HUF - YopH effector protein from Yersinia pestis - N-terminal domain
1LYV - YopH effector protein from Yersinia pestis - catalytic domain
1HY5 - YopE effector protein from Yersinia pestis
1K6Z - SycE molecular chaperone from Yersinia pestis
1ORJ - FliS flagellar chaperone from Aquifex aeolicus
1ORY - FliS flagellar chaperone from Aquifex aeolicus in complex with FliC fragment
1R6F - LcrV (V-antigen) protein from Yersinia pestis

Carbohydrate structure and chemistry
1ELJ - maltodextrin-binding protein from Pyrococcus furiosus

Farnesyl diphosphate synthase
3S4J - Human FDPS in complex with a rigid analog of risedronate
3RYE - Human FDPS in complex with a piridinium bisphosphonate
2RAH - Human FDPS in complex with a novel ligand
2QIS - Human FDPS mutant T210S in complex with risedronate
2VF6 - Human FDPS in complex with minodronate

Kinases
2GHL - Mouse p38 kinase with inhibitor
2GHM - Mouse p38 kinase with inhibitor
2GTM - Mouse p38 kinase with inhibitor
2GTN - Mouse p38 kinase with inhibitor
2HK5 - Human HCK kinase with inhibitor

Method development
1LVB - TEV protease with substrate
1LVM - TEV protease with product
2G6X - Pplu2 novel green fluorescent protein from marine copepod Pontellina plumata
2G6Y - Pplu2 novel green fluorescent protein from marine copepod Pontellina plumata

Nuclear hormone receptors
2HFP - Human PPAR-gamma ligand-binding domain with ligand and co-activator peptide

Prolyl hydroxylases
2HBT - Human EGLN-1 catalytic domain with inhibitor
2HBU - Human EGLN-1 catalytic domain with inhibitor

Protein phosphatases
1LYV - YopH tyrosine phosphatase mutant in complex with phosphate
2F6T - PTP1B tyrosine phosphatase with inhibitor
2F6V - PTP1B tyrosine phosphatase with inhibitor
2F6W - PTP1B tyrosine phosphatase with inhibitor
2F6Y - PTP1B tyrosine phosphatase with inhibitor
2F6Z - PTP1B tyrosine phosphatase with inhibitor
2F70 - PTP1B tyrosine phosphatase with inhibitor
2F71 - PTP1B tyrosine phosphatase with inhibitor
2I5X - PTPbeta tyrosine phosphatase with inhibitor
2H02 - PTPbeta tyrosine phosphatase with inhibitor
2H03 - PTPbeta tyrosine phosphatase with inhibitor
2H04 - PTPbeta tyrosine phosphatase with inhibitor
2HC1 - PTPbeta tyrosine phosphatase with inhibitor
2HC2 - PTPbeta tyrosine phosphatase with inhibitor
2I3R - PTPbeta tyrosine phosphatase with inhibitor
2I3U - PTPbeta tyrosine phosphatase with inhibitor
2I4E - PTPbeta tyrosine phosphatase with inhibitor
2I4G - PTPbeta tyrosine phosphatase with inhibitor
2I4H - PTPbeta tyrosine phosphatase with inhibitor


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