| Anti-bacterial drug discovery |
|
2WIU - HipB in complex with HipA (Escherichia coli) - modified by mercury ions
2VPQ - Biotin carboxylase (Staphylococcus aureus) with AMP-PNP 2VQD - Biotin carboxylase (Pseudomonas aeruginosa) with AMP-PCP 2VR1 - Biotin carboxylase (Escherichia coli) with AMP-PCF2P 2RHQ - Phenylalanine tRNA synthetase in complex with inhibitor 2RHS - Phenylalanine tRNA synthetase in complex with inhibitor 2GG0 - Methionine aminopeptidase with inhibitor 2GG2 - Methionine aminopeptidase with inhibitor 2GG3 - Methionine aminopeptidase with inhibitor 2GG5 - Methionine aminopeptidase with inhibitor 2GG7 - Methionine aminopeptidase with inhibitor 2GG8 - Methionine aminopeptidase with inhibitor 2GG9 - Methionine aminopeptidase with inhibitor 2GGB - Methionine aminopeptidase with inhibitor 2GGC - Methionine aminopeptidase with inhibitor
|
| Bacterial type III secretion and flagellum assembly |
|
1G9U - YopM effector protein from Yersinia pestis
1JL5 - YopM effector protein from Yersinia pestis 1HUF - YopH effector protein from Yersinia pestis - N-terminal domain 1LYV - YopH effector protein from Yersinia pestis - catalytic domain 1HY5 - YopE effector protein from Yersinia pestis 1K6Z - SycE molecular chaperone from Yersinia pestis 1ORJ - FliS flagellar chaperone from Aquifex aeolicus 1ORY - FliS flagellar chaperone from Aquifex aeolicus in complex with FliC fragment 1R6F - LcrV (V-antigen) protein from Yersinia pestis
|
| Carbohydrate structure and chemistry |
|
1ELJ - maltodextrin-binding protein from Pyrococcus furiosus
|
| Farnesyl diphosphate synthase |
|
2RAH - Human FDPS in complex with a novel ligand
2QIS - Human FDPS mutant T210S in complex with risedronate 2VF6 - Human FDPS in complex with minodronate
|
| Kinases |
|
2GHL - Mouse p38 kinase with inhibitor
2GHM - Mouse p38 kinase with inhibitor 2GTM - Mouse p38 kinase with inhibitor 2GTN - Mouse p38 kinase with inhibitor 2HK5 - Human HCK kinase with inhibitor
|
| Method development |
|
1LVB - TEV protease with substrate
1LVM - TEV protease with product 2G6X - Pplu2 novel green fluorescent protein from marine copepod Pontellina plumata 2G6Y - Pplu2 novel green fluorescent protein from marine copepod Pontellina plumata
|
| Nuclear hormone receptors |
|
2HFP - Human PPAR-gamma ligand-binding domain with ligand and co-activator peptide
|
| Prolyl hydroxylases |
|
2HBT - Human EGLN-1 catalytic domain with inhibitor
2HBU - Human EGLN-1 catalytic domain with inhibitor
|
| Protein phosphatases |
|
1LYV - YopH tyrosine phosphatase mutant in complex with phosphate
2F6T - PTP1B tyrosine phosphatase with inhibitor 2F6V - PTP1B tyrosine phosphatase with inhibitor 2F6W - PTP1B tyrosine phosphatase with inhibitor 2F6Y - PTP1B tyrosine phosphatase with inhibitor 2F6Z - PTP1B tyrosine phosphatase with inhibitor 2F70 - PTP1B tyrosine phosphatase with inhibitor 2F71 - PTP1B tyrosine phosphatase with inhibitor 2I5X - PTPbeta tyrosine phosphatase with inhibitor 2H02 - PTPbeta tyrosine phosphatase with inhibitor 2H03 - PTPbeta tyrosine phosphatase with inhibitor 2H04 - PTPbeta tyrosine phosphatase with inhibitor 2HC1 - PTPbeta tyrosine phosphatase with inhibitor 2HC2 - PTPbeta tyrosine phosphatase with inhibitor 2I3R - PTPbeta tyrosine phosphatase with inhibitor 2I3U - PTPbeta tyrosine phosphatase with inhibitor 2I4E - PTPbeta tyrosine phosphatase with inhibitor 2I4G - PTPbeta tyrosine phosphatase with inhibitor 2I4H - PTPbeta tyrosine phosphatase with inhibitor
|